SLC6A1 interacts_with GABA

Subject: SLC6A1
Relation: interacts_with
Object: GABA
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

Genome-Wide Meta-Analysis of Longitudinal Alcohol Consumption Across Youth and Early Adulthood. (2015) PMID:26081443 cited

gene encodes protein GAT-1, which removes GABA from the synaptic cleft

confidence: 0.95

GABAergic gene expression in postmortem hippocampus from alcoholics and cocaine addicts; corresponding findings in alcohol-naïve P and NP rats. (2012) PMID:22253714 cited

SLC6A1 encodes the GAT1 transporter that is responsible for re-uptake of GABA from the synaptic cleft.

confidence: 0.90