GABAA receptor associated_with ethanol dependence
Evidence from:
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Evidence (3 sources)
GABAergic gene expression in postmortem hippocampus from alcoholics and cocaine addicts; corresponding findings in alcohol-naïve P and NP rats.
(2012)
PMID:22253714
cited
changes in the expression of subunits of GABAA receptors are implicated in the development of ... dependence
confidence: 0.95
Associations of glutamate decarboxylase genes with initial sensitivity and age-at-onset of alcohol dependence in the Irish Affected Sib Pair Study of Alcohol Dependence.
(2009)
PMID:19111404
cited
neuroadaptation in the GABAergic system and pharmacological sensitivity of GABA receptors play important roles in ... ethanol dependence
confidence: 0.90
The role of GABA(A) receptors in the acute and chronic effects of ethanol: a decade of progress.
(2009)
PMID:19455309
cited
other studies have also implicated GABAA receptors in ethanol dependence
confidence: 0.90