GABRA2 associated_with ethanol dependence
Evidence from:
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Evidence (3 sources)
Deletion of the gabra2 gene results in hypersensitivity to the acute effects of ethanol but does not alter ethanol self administration.
(2012)
PMID:23115637
cited
Recent evidence suggests that the α2-subunit plays a role in ethanol dependence only in those who have been subjected to childhood trauma.
confidence: 0.90
Deletion of the gabra2 gene results in hypersensitivity to the acute effects of ethanol but does not alter ethanol self administration.
(2012)
PMID:23115637
cited
polymorphisms of the GABRA2 gene ... are associated with ethanol dependence in European American, white American, American plains Indian tribe and Russian populations
confidence: 0.95
The role of GABA(A) receptors in the acute and chronic effects of ethanol: a decade of progress.
(2009)
PMID:19455309
cited
GABRA2 gene ... were associated with both ethanol dependence
confidence: 0.95