naltrexone targets Oprd1

Subject: naltrexone
Relation: targets
Object: Oprd1
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

Diagnosis and Pharmacotherapy of Alcohol Use Disorder: A Review. (2018) PMID:30167705 cited

Naltrexone is a non-selective antagonist of mu, kappa, and delta opioid receptors

confidence: 0.98

Delta and kappa opioid receptor polymorphisms influence the effects of naltrexone on subjective responses to alcohol. (2012) PMID:22954510 cited

delta receptor blockade was lower (about 21%) but also highly variable

confidence: 0.90