OPRM1 A118G associated_with abstinence
Evidence from:
primary |
all sources
Evidence (2 sources)
A clinical trial by Lerman et al. found that NRT patients carrying the G allele had better abstinence rates than A/A patients when treated with transdermal patches.
confidence: 0.88
Nicotine withdrawal sensitivity, linkage to chr6q26, and association of OPRM1 SNPs in the SMOking in FAMilies (SMOFAM) sample.
(2009)
PMID:19959688
cited
smokers with one or more copies of the major allele (G) were more likely to be abstinent compared to smokers with two copies of the minor allele
confidence: 0.91