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OPRM1 interacts_with OPRK1

Subject
OPRM1
Relation
interacts_with
Object
OPRK1
p-value
Evidence from: primary | all sources

Evidence (2 sources)

The genetics of alcohol dependence: advancing towards systems-based approaches. (2012) PMID:22854292 cited
Kumar et al. discovered epistatic effects between the mu and kappa opioid system.
confidence: 0.90
The genetics of alcohol dependence: advancing towards systems-based approaches. (2012) PMID:22854292 cited
Kumar et al. discovered epistatic effects between the mu and kappa opioid system, with respect to alcohol... locus-locus interactions between OPRM1 and OPRK1 led to a two-fold increase (2.318, 1.025 to 5.24) in the risk for alcoholism.
confidence: 0.95