5-HTTLPR associated_with depression

Subject: 5-HTTLPR
Relation: associated_with
Object: depression
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

Candidate gene-environment interaction research: reflections and recommendations. (2015) PMID:25620996 primary

association between the short allele of 5HTTLPR and depression is strongest in individuals experiencing major stressful life events

confidence: 0.88

Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis. (2009) PMID:19531786 cited

the L allele was associated with stressful life events and depression

confidence: 0.90