picrotoxin targets GABAA receptor

Subject: picrotoxin
Relation: targets
Object: GABAA receptor
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

Sustained synchronized neuronal network activity in a human astrocyte co-culture system. (2016) PMID:27819315 cited

picrotoxin (GABAA receptor inhibitor)

confidence: 0.96

Adolescent chronic mild stress alters hippocampal CB1 receptor-mediated excitatory neurotransmission and plasticity. (2013) PMID:24035826 cited

we used a relatively weak concentration of PTX (50 μM) to partially block GABA(A) receptors

confidence: 0.95