CHRNA5-CHRNA3-CHRNB4 cluster associated_with nicotine
Evidence from:
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Evidence (3 sources)
Genome-wide search for replicable risk gene regions in alcohol and nicotine co-dependence.
(2012)
PMID:22488850
cited
CHRNA5-CHRNA3-CHRNB4 ... have previously been associated to both alcohol and nicotine dependence
confidence: 0.95
Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes.
(2012)
PMID:22290489
cited
association of the CHRNA5-CHRNA3-CHRNB4 gene cluster with nicotine dependence phenotypes
confidence: 0.96
Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans.
(2010)
PMID:20584212
cited
some of these variants also affect nicotine dependence ... in Asians
confidence: 0.96