CREBBP risk_factor_for drug dependence

Subject: CREBBP
Relation: risk_factor_for
Object: drug dependence
p-value: —

Evidence from: primary | all sources

Evidence (1 sources)

KAT2B polymorphism identified for drug abuse in African Americans with regulatory links to drug abuse pathways in human prefrontal cortex. (2016) PMID:26202629 primary

reduced CREBBP expression would decrease susceptibility to abusing drugs, implying higher expression increases risk

confidence: 0.75