SIRT1 regulates SREBF1

Subject: SIRT1
Relation: regulates
Object: SREBF1
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

Peroxisome proliferator-activated receptor and retinoic x receptor in alcoholic liver disease. (2009) PMID:19756185 cited

inhibition of hepatic SIRT1 activity is associated with an increase in the acetylated active nuclear form of SREBP-1c

confidence: 0.90

Peroxisome proliferator-activated receptor and retinoic x receptor in alcoholic liver disease. (2009) PMID:19756185 cited

SIRT-1 mediates SREBP-1 activation by ethanol

confidence: 0.90