WIN55,212-2 targets CB1 receptor

Subject: WIN55,212-2
Relation: targets
Object: CB1 receptor
p-value: —

Evidence from: primary | all sources

Evidence (3 sources)

Adolescent chronic mild stress alters hippocampal CB1 receptor-mediated excitatory neurotransmission and plasticity. (2013) PMID:24035826 cited

WIN effect ... CB1-dependent, and CB1 is encoded by CNR1.

confidence: 0.75

Adolescent chronic mild stress alters hippocampal CB1 receptor-mediated excitatory neurotransmission and plasticity. (2013) PMID:24035826 cited

WIN-induced increase in fEPSP magnitude in CMS animals is enhanced CB1 function

confidence: 0.90

Adolescent chronic mild stress alters hippocampal CB1 receptor-mediated excitatory neurotransmission and plasticity. (2013) PMID:24035826 cited

Blocking CB1 with AM251 prevents the WIN effects on fEPSP magnitude... demonstrating that these effects are CB1 dependent.

confidence: 0.95