OPRM1 risk_factor_for drug dependence
Evidence from:
primary |
all sources
Evidence (3 sources)
KAT2B polymorphism identified for drug abuse in African Americans with regulatory links to drug abuse pathways in human prefrontal cortex.
(2016)
PMID:26202629
primary
OPRM1 gene has long been suspected to influence susceptibility to drug addiction
confidence: 0.90
The endogenous opioid system plays a key role in drug addiction, and ... receptors encoded by OPRM1 ...
confidence: 0.60
Meta-analysis and genome-wide interpretation of genetic susceptibility to drug addiction.
(2011)
PMID:21999673
cited
These addiction susceptible genes are enriched ... that had been previously reported to be involved in drug addiction.
confidence: 0.90