ethanol group regulates Gabra4
Evidence from:
primary |
all sources
Evidence (8 sources)
no change in the internalization of α4 GABAA receptors ... significant increase in α4 subunit peptide
confidence: 0.80
increases levels of α4 subunit mRNA in hippocampus
confidence: 0.90
significant increase in α4 subunit peptide ... following chronic EtOH exposure
confidence: 0.95
The role of GABA(A) receptors in the acute and chronic effects of ethanol: a decade of progress.
(2009)
PMID:19455309
cited
chronic ethanol consumption ... increases ... α4 subunit peptide expression
confidence: 0.90
Associations of glutamate decarboxylase genes with initial sensitivity and age-at-onset of alcohol dependence in the Irish Affected Sib Pair Study of Alcohol Dependence.
(2009)
PMID:19111404
cited
GABAAα4 subunit expression ... were significantly increased ... after chronic ethanol administration
confidence: 0.90
The role of GABA(A) receptors in the acute and chronic effects of ethanol: a decade of progress.
(2009)
PMID:19455309
cited
Chronic ethanol exposure ... increases ... α4 ... subunit mRNA/peptide levels in cerebral cortex
confidence: 0.92
The role of GABA(A) receptors in the acute and chronic effects of ethanol: a decade of progress.
(2009)
PMID:19455309
cited
Chronic ethanol exposure increases expression of α4 at the cell surface
confidence: 0.93
The role of GABA(A) receptors in the acute and chronic effects of ethanol: a decade of progress.
(2009)
PMID:19455309
cited
GABAA receptor ligands with selectivity for α4‑GABAA receptors ... translocation of α4‑GABAA receptors ... mechanism of adaptation to ethanol exposure
confidence: 0.80