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OPRM1 A118G associated_with OPRM1

Subject
OPRM1 A118G
Relation
associated_with
Object
OPRM1
p-value
Evidence from: primary | all sources

Evidence (19 sources)

Multi-trait genome-wide association study of opioid addiction: OPRM1 and beyond. (2022) PMID:36207451 primary
Separate analyses conditioning on rs1799971 ... to assess the interdependence of OPRM1 signals.
confidence: 0.90
Multi-trait genome-wide association study of opioid addiction: OPRM1 and beyond. (2022) PMID:36207451 primary
The variant identified is the long‑studied rs1799971 (OPRM1‑A118G), a functional coding variant ... in the mu opioid receptor gene (OPRM1).
confidence: 0.96
Differential sensitivity of human neurons carrying μ opioid receptor (MOR) N40D variants in response to ethanol. (2020) PMID:32561311 primary
major functional OPRM1 SNP
confidence: 0.80
Review: Pharmacogenetics of alcoholism treatment: Implications of ethnic diversity. (2017) PMID:28134463 cited
Asp40 carriers of the OPRM1 gene ...
confidence: 0.95
Review: Pharmacogenetics of alcoholism treatment: Implications of ethnic diversity. (2017) PMID:28134463 cited
The most frequently studied polymorphism is the Asn40Asp SNP of the OPRM1 gene.
confidence: 0.95
Brain region- and sex-specific alterations in DAMGO-stimulated [(35) S]GTPγS binding in mice with Oprm1 A112G. (2014) PMID:22862850 cited
The A118G single nucleotide polymorphism (SNP) of the human µ opioid receptor gene (OPRM1)...
confidence: 0.96
Pharmacogenetics of OPRM1. (2014) PMID:24201053 cited
The small number of pharmacogenetic studies analyzing the role of OPRM1 in nicotine dependence treatment have focused on the A118G polymorphism.
confidence: 0.95
Brain region- and sex-specific alterations in DAMGO-stimulated [(35) S]GTPγS binding in mice with Oprm1 A112G. (2014) PMID:22862850 cited
first exon of the human MOPR gene with A118 and G118
confidence: 0.90
Preliminary evidence for a gene-environment interaction in predicting alcohol use disorders in adolescents. (2013) PMID:23136901 cited
The A118G SNP in the OPRM1 gene was assayed using a commercially available instrument and TaqMan assays.
confidence: 0.95
The genetics of the opioid system and specific drug addictions. (2012) PMID:22547174 cited
The most studied OPRM1 variant is the non-synonymous variant rs1799971 (118A>G, Asn40Asp).
confidence: 0.98
Delta and kappa opioid receptor polymorphisms influence the effects of naltrexone on subjective responses to alcohol. (2012) PMID:22954510 cited
A118G SNP of the OPRM1 gene
confidence: 0.96
Delta and kappa opioid receptor polymorphisms influence the effects of naltrexone on subjective responses to alcohol. (2012) PMID:22954510 cited
participants were prospectively genotyped at the A118G variant of OPRM1.
confidence: 0.95
The genetics of the opioid system and specific drug addictions. (2012) PMID:22547174 cited
As the 118A>G SNP changes an amino acid, it has been generally assumed that it is the causative variant for the phenotypes associated with it.
confidence: 0.96
Delta and kappa opioid receptor polymorphisms influence the effects of naltrexone on subjective responses to alcohol. (2012) PMID:22954510 cited
in addition to the A118G SNP of the OPRM1
confidence: 0.95
Delta and kappa opioid receptor polymorphisms influence the effects of naltrexone on subjective responses to alcohol. (2012) PMID:22954510 cited
prospective genotyping based on the A118G SNP of the OPRM1 gene
confidence: 0.94
The genetic basis of addictive disorders. (2012) PMID:22640768 cited
a common functional missense variant of the μ-opioid receptor (OPRM1 Asn40Asp)
confidence: 0.96
A genetic determinant of the striatal dopamine response to alcohol in men. (2011) PMID:20479755 cited
individuals carrying one or two copies of the variant 118G allele (118AG or 118GG genotype ...) of the OPRM1 polymorphism
confidence: 0.96
Haplotype block structure of the genomic region of the mu opioid receptor gene. (2011) PMID:21160491 cited
The non-synonymous variant rs1799971 (118A>G, Asn40Asp) ...
confidence: 0.96
Lack of association between the A118G polymorphism of the mu opioid receptor gene (OPRM1) and opioid dependence: A meta-analysis. (2009) PMID:23226031 cited
The most frequently studied OPRM1 variant is the single nucleotide polymorphism (SNP) A118G ... in exon 1
confidence: 0.95