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baclofen protective_against alcohol dependence

Subject
baclofen
Relation
protective_against
Object
alcohol dependence
p-value
Evidence from: primary | all sources

Evidence (2 sources)

Diagnosis and Pharmacotherapy of Alcohol Use Disorder: A Review. (2018) PMID:30167705 cited
In 2014, it was given a temporary recommendation in France for treating alcohol dependence.
confidence: 0.90
Altered gamma-aminobutyric acid type B receptor subunit 1 splicing in alcoholics. (2014) PMID:24209778 cited
drugs acting on GABAB receptors have been used for alcoholism treatment; baclofen may be effective at high doses
confidence: 0.85