rs1051730 associated_with Chrnb4
Evidence from:
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Evidence (5 sources)
Genetic variability in the regulation of gene expression in ten regions of the human brain.
(2014)
PMID:25174004
cited
region of high linkage disequilibrium that covers the related genes CHRNA5 and CHRNB4
confidence: 0.85
TTC12-ANKK1-DRD2 and CHRNA5-CHRNA3-CHRNB4 influence different pathways leading to smoking behavior from adolescence to mid-adulthood.
(2011)
PMID:21168125
cited
for CHRNA5-CHRNA3-CHRNB4, the most significantly associated allele was rs1051730[A].
confidence: 0.85
Variants in nicotinic acetylcholine receptors alpha5 and alpha3 increase risks to nicotine dependence.
(2009)
PMID:19132693
cited
the association signal observed at rs1051730 ... could extend to CHRNB4 gene
confidence: 0.90
Variants in nicotinic acetylcholine receptors alpha5 and alpha3 increase risks to nicotine dependence.
(2009)
PMID:19132693
cited
the association signal observed at rs16969968 and rs1051730 could extend to CHRNB4 gene
confidence: 0.75
A common genetic variant in the 15q24 nicotinic acetylcholine receptor gene cluster (CHRNA5-CHRNA3-CHRNB4) is associated with a reduced ability of women to quit smoking in pregnancy.
(2009)
PMID:19429911
cited
rs1051730 SNP in the CHRNA5–CHRNA3–CHRNB4 gene cluster
confidence: 0.95