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microglial activation associated_with Alcohol Use Disorder

Subject
microglial activation
Relation
associated_with
Object
Alcohol Use Disorder
p-value
Evidence from: primary | all sources

Evidence (2 sources)

Integrated single-cell multiomic profiling of caudate nucleus suggests key mechanisms in alcohol use disorder. (2025) PMID:41083468 primary
higher proportion of Inflammatory Microglia (subcluster 2) in individuals with AUD: 31%, versus 23% in those without
confidence: 0.90
Integrated Single-Cell Multiomic Profiling of Caudate Nucleus Suggests Key Mechanisms in Alcohol Use Disorder. (2024) PMID:39149227 primary
70% of individuals with at least half of their microglia in the inflammatory state had AUD, versus 52% with lower inflammatory state.
confidence: 0.88