ethanol group targets GABAA receptor
Evidence from:
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all sources
Evidence (3 sources)
EtOH potentiation of GABAergic synaptic inhibition ... postsynaptic effects result from potentiation of GABAA/anion channels.
confidence: 0.96
Deletion of the gabra2 gene results in hypersensitivity to the acute effects of ethanol but does not alter ethanol self administration.
(2012)
PMID:23115637
cited
GABAA receptors have been suggested to represent a primary target for ethanol
confidence: 0.80
GABA A receptors: subtypes provide diversity of function and pharmacology.
(2009)
PMID:18760291
cited
as well as ethanol ... can be used for the identification of specific GABAA receptor subtypes.
confidence: 0.95