rare variant risk_factor_for bipolar disorder

Subject: rare variant
Relation: risk_factor_for
Object: bipolar disorder
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

What Should a Psychiatrist Know About Genetics? Review and Recommendations From the Residency Education Committee of the International Society of Psychiatric Genetics. (2018) PMID:30549495 cited

up to 3%−5% of cases of bipolar illness

confidence: 0.95

CNVs: harbingers of a rare variant revolution in psychiatric genetics. (2012) PMID:22424231 cited

Results from early CNV studies suggest that rare variants play a role in bipolar disorder (Malhotra et al., 2011; Priebe et al., 2011; Zhang et al., 2009a).

confidence: 0.90