OPRM1 A118G protective_against opioid dependence
Evidence from:
primary |
all sources
Evidence (3 sources)
Multi-trait genome-wide association study of opioid addiction: OPRM1 and beyond.
(2022)
PMID:36207451
primary
The rs1799971‑G protective association with OA was identified (discovery p = 1.51 × 10⁻⁸, replication p = 0.049).
confidence: 0.98
The 118G allele was found to be protective against opioid dependence in a cohort of Malaysians
confidence: 0.95
The 118G allele was found to be protective against opioid dependence in a cohort of Malaysians
confidence: 0.90