ALDH2 regulates acetic acid
Evidence from:
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Evidence (4 sources)
enzyme responsible for metabolizing acetaldehyde (a metabolite of alcohol) to acetic acid.
confidence: 0.95
The genetics of alcohol dependence: advancing towards systems-based approaches.
(2012)
PMID:22854292
cited
the liver enzymes, ... aldehyde dehydrogenase (ALDH) regulate the degradation of alcohol into acetate.
confidence: 0.96
Peroxisome proliferator-activated receptor and retinoic x receptor in alcoholic liver disease.
(2009)
PMID:19756185
cited
Reduced ALDH activity observed in RXR deficient mice impairs the further oxidation to acetate.
confidence: 0.90
The genetics of alcohol metabolism: role of alcohol dehydrogenase and aldehyde dehydrogenase variants.
(2007)
PMID:17718394
cited
the inactive ALDH2*2 allele ... no longer oxidizes acetaldehyde to acetate
confidence: 0.93