Dopamine D2 receptor risk_factor_for alcohol dependence

Subject: Dopamine D2 receptor
Relation: risk_factor_for
Object: alcohol dependence
p-value: —

Evidence from: primary | all sources

Evidence (3 sources)

Genome-wide association discoveries of alcohol dependence. (2014) PMID:25278008 cited

classical neurotransmitter signaling systems (e.g., NCAM1‑TTC12‑ANKK1‑DRD2) are risk genes for alcohol dependence

confidence: 0.95

TTC12-ANKK1-DRD2 and CHRNA5-CHRNA3-CHRNB4 influence different pathways leading to smoking behavior from adolescence to mid-adulthood. (2011) PMID:21168125 cited

DRD2 ... has been linked to ... alcohol ... dependencies

confidence: 0.90

Behavioral and biological indicators of impulsivity in the development of alcohol use, problems, and disorders. (2010) PMID:20491733 cited

could be partly mediated by the DRD2 gene

confidence: 0.85