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Chunk #15 — SUSCEPTIBILITY LOCI AND GENES OF COMPLEX NEURODEVELOPMENTAL DISORDERS — Schizophrenia

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Genetic and environmental factors in complex neurodevelopmental disorders.
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Schizophrenia is a common mental disorder affecting approximately 1% of the population [14]. It generally emerges between 16 and 30 years of age and is characterized by three main symptoms: cognitive disturbances, psychosis and negative symptoms [15]. Unfortunately, there are no genetic markers available for diagnosing schizophrenia. Therefore, diagnosis can only be based on clinical symptoms using the Diagnostic and Statistical manual for mental disorders version IV (DSM-IV, 2000) or the International Classification of Disease version 10 (ICD-10, 1992).