3q21.3-q29, 4q21.3-q35.1, 5p12-p15.33, 6q14.3-q23.2, 7q21.2q36.2, 10p12.1-p14, 10q23.3-q26.3, 13q12.13-q33.1, 15q13.1-q26.1, 16p12.1-p13.3, 17q11.1-q21.2, 19p13.11-p13.3 and 19q12-q13.12 [reviewed in 10]. Although most susceptibility regions have been studied in more detail via the candidate-gene approach (e.g. the Reelin gene on chromosome 7q22 and the serotonin transporter gene (SLC6A4) on chromosome 17q11.1-q12), no gene has been found to clearly contribute to autism susceptibility. Recently, the first GWA studies for autism have been reported with significant associations, including CNVs, found in several genetic loci [11-13], but the results have been inconclusive. Thus, despite the high heritability estimates for autism, its genetic aetiology still needs to be elucidated.
