We chose nine phenotypes with low phenotypic correlation and sample overlap: Height, BMI, menarche, LDL levels, coronary artery disease, schizophrenia, educational attainment, smoking behavior, and rheumatoid arthritis (see Supplementary Note). We performed a random-effects meta-analysis of proportion of heritability over the nine phenotypes listed above for each functional category. The results are in Figure 4 and Supplementary Table 4. Results meta-analyzed over all 17 traits are in Supplementary Figure 9; however these results have artificially deflated standard errors due to correlated traits such as HDL/LDL/Triglycerides being treated as independent.
