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Chunk #20 — Results — Groups defined by hierarchical clustering of global transcriptional profiles

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Transcriptional changes common to human cocaine, cannabis and phencyclidine abuse.
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Overall, a past or present abuse of cocaine was indicated by the drug abuse history and/or general and hair toxicology for a large proportion (32/42, 76%) of the cases ( Fig. 1 , Table 2 , Table S1 ). Significant blood alcohol levels (≥0.05 g/dL (g%)) were more prominent in Group I (9/18, 50%) than in Group II cases (3/16, 19%). Conversely, opioids were not found in Group I cases, but were present in 5/16 (31%) Group II cases. Furthermore, Group II contained 5/9 (56%) of the phencyclidine cases, while Group I and Group II each had two cases (22%).