Group III cases appeared different from Group I and Group II cases, in that they represented cases with no or only residual cocaine, cannabis or phencyclidine and metabolites, presented with significant other medical circumstances, such as anaphylactic shock, major depression, suicide completion, and organic disease related to chronic alcoholism. Five cases (DA36, DA38–41) were primarily described as alcohol dependent. The three remaining cases (DA35, DA37, DA42) were characterized as cannabis users by history, but general toxicology and hair testing found additional substances, while neuropathological examination revealed cerebral ischemic changes and/or brain edema.
