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Chunk #16 — RESULTS — Intranetwork and Internetwork Connectivity: Family History

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Association Between Age and Familial Risk for Alcoholism on Functional Connectivity in Adolescence.
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No significant associations emerged between FNC correlations reflecting internetwork connectivity and family history status, although there was one significant effect for intranetwork connectivity after FDR correction. Within a sensorimotor network (comonent 9), FHP participants showed lower intranetwork connectivity compared to FHN individuals (Figure 3). The focus point is within the precentral gyrus and corresponds to premotor cortex near Brodmann area 6 (BA6) (x = 23.5, y = 21.5, z = 62.5). This effect was significant after controlling for parental education and after controlling for IQ (see Figures S1 and S2, available online). There were no significant main effects for age on intranetwork connectivity. Also, there were no significant effects for intranetwork or internetwork connectivity for age group × family history. In addition, although there were significant main effects for sex on intranetwork and internetwork connectivity (see Figures S3 and S4, available online), there was no sex × family history group interaction.