Chi-square allelic association analysis found rs1076560 to be nominally associated with opioid dependence in the AA population (χ2=4.85, 1 d.f., p=0.03, OR=1.43) with the minor allele over-represented in cases. rs1076560 was also found to be nominally associated with opioid dependence in the EA population; (χ2=5.57, p=0.02, OR=1.27) however, a lower OR was observed (Table 1). No significant associations with cocaine dependence were found in the AA population (χ2=1.75, p=0.19, OR=1.18) or the EA population (χ2=1.42, p=0.23, OR=1.17) (Table 1).
