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Chunk #10 — 2. METHODS AND MATERIALS — 2.1. Subjects

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Reduced resource optimization in male alcoholics: N400 in a lexical decision paradigm.
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All the subjects were right handed and had at least a minimum of ten years of education. In the alcohol dependent group, some subjects also had a history of other substance abuse. This comorbid poly-substance use/abuse is commonly observed in alcohol dependent subjects, especially in the US population (Bierut et al., 1998; Compton et al., 2007; Hasin et al., 2007). Assessments, recordings and analyses were conducted at the State University of New York – Downstate Medical Center and the study was approved by the Institutional Review Board (IRB).