Reduced connectivity among insula, precuneus, SMA, postcentral, lingual/vermis and fusiform gyri characterized the rsFNCs driven by drinking. These results are consistent with previous hypoconnectivity observations in visual and sensorimotor areas (Weiland et al., 2014). Our analysis also pointed to the precuneus as an area associated with alcohol use disorders as it has been previously found (Claus et al., 2011). Abnormal activation in the precuneus of subjects with alcohol use disorder has been thought to be associated with craving and the processing of visual memories (Park et al., 2007). In our results, sensorimotor, precuneus and visual dysfunctions seem ubiquitous in both smokers and drinkers after looking at the rsFNCs driven by smoking and drinking. However, we point out that visual dysfunction associated to drinking in our data were located around fusiform and lingual gyri. In contrast, rsFNC differences driven by both smoking and drinking were more frequently located about superior, middle and inferior occipital gyri. These results agree with an alcohol study by Camchong et al. (Camchong et al., 2012) where reduced connectivity within insula and within occipital gyrus was reported,
