Moreover, taking advantage of this catalog, we searched for variants mapping the UTRs that affect disease risk and/or quantitative parameters. For instance, among diseases, genetic variants at UTRs are more frequently associated with immunological, neoplastic and neurological pathologies (figure 1, panel A). Similarly, among the quantitative traits, we observed that the large part of known UTR associations were involved in immune-related, haematological, anatomical parameters and metabolic traits, while a small number of variants affect inflammatory and cardiological phenotypes (figure 1, panel B).
