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Chunk #61 — WHAT IS KNOWN FROM GWAS STUDIES

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Genetic variants in mRNA untranslated regions.
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Thus, almost 80% of the UTR associated variants reported in the literature are localised in the 3′UTR region. However, as the 3′UTRs are, on average, much longer than 5′UTRs, we adjusted the number of identified variants per the UTRs length, observing a comparable number of associated variants in both UTRs (table 2). These estimations were obtained by exploiting genomic data from the Ensembl database (http://grch37.ensembl.org/biomart/, database: Ensembl Genes 91, dataset: Human Genes - GRCh37.p13).