Input/output recordings were measured for both KAR-mediated EPSCs and fEPSPs. For both types of recording, input/output values were collected using increasing stimulus intensities for each cell or slice. At each stimulus intensity, EPSC amplitude or fEPSP slope was measured and compared across the treatment conditions. All values were expressed as mean response area (for EPSCs) or percent control (for fEPSPs) ± SEM, and data were subjected to a two-way ANOVA with stimulus intensity and fEPSP slope as the main dependent variables with Bonferroni post-hoc analyses; P<0.05 was considered statistically significant.
