Genetically and geographically isolated populations provide several advantages for studying genes related to complex diseases. The CVCR population is a recently founded population, which displays similar features to other genetic isolates with few founders, therefore presenting a homogenous population suitable for studying genes underlying complex genetic disorders. In fact, chromosomal areas of interest have already been identified in this cohort for both SZ (Cooper-Casey et al., 2005; DeLisi et al., 2002; Walss-Bass et al., 2006) and BD (Freimer et al., 1996).
