transcription factors and other aspects of transcriptional regulation. For Molecular Function, categories '0003700' (transcription factor activity) and '0003714' (transcription corepressor activity), with 497 and 74 genes, respectively, were just beyond the FDR significance cutoff with adjusted p-values of 0.056 and 0.078 (Additional File 3). For Cellular Component, nearly all significant categories were directly related to various aspects or cell-type specific (e.g. neuronal) specializations of the cellular membrane (9 of 13 hits at q = 0.05).