We further analyzed the creQTL results with Gene Ontology in order to determine if any broad categories of genes participated in the regulation of gene clusters. There were 648, 176, and 310 Gene Ontology Biological Process (BP), Cellular Component (CC), and Molecular Function (MF) annotations, respectively, for gene set enrichment testing that were represented on the SNP arrays after assigning the 68,523 SNPs to 8,398 protein-coding genes in cis, using an arbitrary minimum cutoff of 10 genes for a category to be tested. Top hits are shown in Table 3 at a more relaxed q = 0.05. The most significant ontologies were related to cell adhesion, potassium- and calcium ion transport, binding, channel activity, development, and the nervous system, particularly development and plasticity. For Biological Process and Molecular Function, as expected, some of the most enriched categories were related to transcription factors and other aspects of transcriptional regulation. For Molecular Function, categories '0003700' (transcription factor activity) and '0003714' (transcription corepressor activity), with 497 and 74 genes, respectively, were just beyond the FDR significance cutoff with adjusted p-values of 0.056 and
