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Chunk #13 — Methods — Quality Control

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AUDIT-C and ICD codes as phenotypes for harmful alcohol use: association with ADH1B polymorphisms in two US populations.
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Because trajectory analysis, one of the analytic methods used herein, requires repeated measures, we only included individuals with two or more AUDIT-C scores obtained at different ages. This approach yielded an analytic sample of 167,721 participants (57,677 AAs and 110,044 EAs). The sample was predominantly male (92%), with a mean age of 63 years at sampling and a median of seven AUDIT-C scores per subject (25th and 75th quartiles: 5 and 8).