DSM-IV included nicotine dependence, but experts felt that abuse criteria were inapplicable to nicotine (163, 164), so these were not included. Nicotine dependence has good test-retest reliability (165–167) and its criteria indicate a unidimensional latent trait (39, 40, 62, 67, 168). Concerns about DSM-IV-defined nicotine dependence include the utility of some criteria, the ability to predict treatment outcome, and low prevalence in smokers (131, 163, 169). Many studies therefore indicate nicotine dependence with an alternative measure, the Fagerström Nicotine Dependence Scale (170, 171). DSM-IV and the Fagerström scale measure somewhat different aspects of a common underlying trait (67, 168, 172).