Chunk #35 — Findings — Improvements in PLINK 1.9 — Other noteworthy algorithms — Hardy-Weinberg equilibrium and Fisher’s exact tests

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Second-generation PLINK: rising to the challenge of larger and richer datasets.

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yes

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Standalone source code for early-termination SNP-HWE and Fisher’s 2×2/ 2×3 exact test is posted at [18]. Due to recent calls for use of mid-p adjustments in biostatistics [19,20], all of these functions have mid-p modes, and PLINK 1.9 exposes them.