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Chunk #37 — Discussion

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Mechanisms in the relation between GABRA2 and adolescent externalizing problems.
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We sought to examine whether impulsivity and/or sensation seeking mediated the relations between GABRA2 genotype and adolescent alcohol problems, conduct problems, and hyperactive–inattentive symptoms. To accomplish this goal, we used a multiple reporter methodology and a high-risk sample in which these relations might be more clearly illuminated due to greater variability in study constructs.