Sensation seeking mediated the relation between GABRA2 genotype and alcohol problems both with and without controlling for T1 alcohol problems (CI95 −1.30, −0.04; CI95 −1.26, −0.07). Impulsivity mediated the relations between GABRA2 and alcohol problems both with and without controlling for T1 alcohol problems (CI95 −0.90, 0.003; CI95 −0.99, −0.07), conduct problems both with and without controlling for T1 conduct problems (CI95 −0.62, −0.04; CI95 −1.07, −0.14), and hyperactive–inattentive symptoms both with and without controlling T1 hyperactive–inattentive symptoms (CI95 −0.11, −0.01; CI95 −0.17, −0.03).
