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Chunk #6 — Materials and Methods — Selection of mirSNPs

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PASSPORT-seq: A Novel High-Throughput Bioassay to Functionally Test Polymorphisms in Micro-RNA Target Sites.
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in Supplementary Table 1. Similarly, 111 mirSNPs located in the 3′ UTR regions of 17 pharmacogenes- the core absorption, distribution, metabolism, and excretion (ADME) genes1, PXR, CAR, and HNF4α which showed allele specific expression in the sequencing dataset were selected to demonstrate the application of the assay. The list of these 111 SNPs are listed in Supplementary Table 4. The RNA analysis and genotyping was approved by the Indiana University Institutional Review Board.