In order to link the identified eQTLs to disease, we made a selection of significant cis effects in the eQTL discovery set. Recent studies on the genetics of gene expression have shown that disease-associated loci from GWAS are greatly enriched for eQTLs [20], [25]. Thus, we selected SNP-transcript pairs that had a nominal SNP p value <0.05 in our GWAS discovery data (Figure 1).
