To further explore the recent increases in mortality among black and Latino individuals, we compared age-specific rates in 2013 to 2016 with those in 2009 to 2012. We found that the largest absolute increases occurred between the ages of 60 and 64 years among Latino men (2009-2012: 45.8 deaths per 100 000 residents; 2013-2016: 54.7 deaths per 100 000 residents), between the ages of 65 and 69 years among black men (2009-2012: 31.4 deaths per 100 000 residents; 2013-2016: 35.7 deaths per 100 000 residents) and between the ages of 55 and 59 years among black women (2009-2012: 8.4 deaths per 100 000 residents; 2013-2016: 11.8 deaths per 100 000 residents) (eFigure 2 in the Supplement).