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Chunk #17 — Biological Pathway Enrichment Analysis

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Genome-wide SNP and CNV analysis identifies common and low-frequency variants associated with severe early-onset obesity.
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Using the Database for Annotation, Visualization and Integrated Discovery (DAVID, see URLs), gene lists were mapped onto curated biological processes gene categories using Gene Ontology (GO, The Gene Ontology Consortium). Gene lists were also mapped to pathways and biological processes using the PANTHER classification system (see URLs) and Ingenuity Pathway Analysis (IPA, version 9.0, Ingenuity Systems, see URLs). The most significantly enriched categories of molecules and pathways (smallest p-values, p<0.05) were identified using these tools.