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Chunk #18 — RESULTS — Mosaic anomalies characteristic of hematological cancers

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Detectable clonal mosaicism from birth to old age and its relationship to cancer.
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two genes, one of which is DNMT3A, recently found to be commonly mutated in AML-M523. (4) On 22q, 11 deletions have a CDR of 153 kb, which includes three genes, one of which is PRAME, which is frequently deleted in CLL24. (5) On 20q, 46 deletions have a CDR of 965 kb, containing 7 genes including L3MBTL1, which is a candidate tumor suppressor in del(20q12) myeloid disorders25.