The major points discussed above are mainly based on findings of altered resting connectivity in addicts compared with non-addicted controls. However, as the roles of resting-state functional connectivity in the circuits implicated in addiction, such as those related reward and craving, remains to be elucidated and due to the lack of behavior tasks in the present study, to what extent the present findings are related to the abnormal brain function in drug addicts is still an open question. Thus, future studies focused on the implications of resting-state functional connectivity in brain circuits of reward, craving and cognitive control, especially in those of drug addicts, are needed to provide a more specific and definitive interpretation of the results in the present study.
