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Chunk #22 — Results — Pathway Analysis of Cardiff SNP Data

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Investigating the contribution of common genetic variants to the risk and pathogenesis of ADHD.
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In the ALIGATOR analysis of our GWAS data set, 315 pathways were enriched at p<0.05 and 81 at p<0.01. More categories were enriched at the more stringent threshold (p=0.033) given the distribution of p values in the genes in the data set as a whole, but none was significant after correcting for multiple testing. Enrichment p values for the top 100 significant pathways are listed in Table S4 in the online data supplement.